It’s unlikely plain acrylic would trip the sawstop (there are some weird edge cases involving static buildup, but the manual doesn’t recommend against it) but it has a nasty habit of shattering and throwing shrapnel if you’re not careful. A bandsaw would be safer, assuming your pieces fit. Or a tracksaw. Or the CNC, or a laser cutter. Or a handheld router. lots of options
If you do use the tablesaw, you can reduce the risk of chip-out by cutting partway through, then flipping the sheet to finish the cut from the other side.
You definitely can’t cut mirrored or anti-static plastics on the sawstop - both of those have conductive components.